Seagen
Director Clinical Pharmacology and Pharmacometrics
Translational Sciences - Bothell, Washington - Seattle, Washington - South San Francisco, California
Description
Summary
The Director of Clinical Pharmacology and Pharmacometrics will have strong technical and leadership skills to develop and implement clinical pharmacology and modeling & simulation (M&S) strategies to advance development of novel oncology drug candidates across various stages of development for multiple modalities. We expect this person to develop and apply quantitative frameworks that enable model-informed drug discovery and development (MIDD) across programs. In addition, this position will ensure quantitative rigor and quality results through direct scientific mentorship.
Key responsibilities:
- Accountable for developing a culture encouraging of MIDD approaches at Seattle Genetics, educating and influencing key partners, stakeholders and regulators of its value and application
- By using state of the art M&S methodologies strongly contribute to decision making at critical milestones based on quantitative principles in close collaboration with Biostats, Clin Pharm and other quantitative disciplines
- Represents Clinical Pharmacology and M&S on cross-functional drug development teams, proactively advocating model-based approaches to address development challenges
- Conduct population PK, PK/PD, exposure-response analyses and other model-based analyses using pharmacostatistical and relevant state of the art modeling and simulation techniques to support dose selection, trial design, Go/No-Go decisions, regulatory submission documents, and publications
- Strengthen our internal M&S capability on a continuous basis by initiating training activities, evaluating and incorporating new M&S tools as appropriate
- Accountable to provide peer review and mentoring and supervision of junior staff
- Coordinate outsourced M&S activities when appropriate
- Monitoring external and internal environment in terms of relevant new methodologies and applications
As the leading employer in our industry in the Pacific Northwest, Seagen is proud to offer a competitive total compensation package as well as a comprehensive benefits program designed to support the whole lives of our employees and their families. Benefits include medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more. To learn more about Seagen, please visit www.seagen.com.
Seagen is an equal opportunity employer. All qualified applications will receive consideration for employment without regard to race, age, gender identity, sexual orientation, color, religion, sex, marital status, national origin, protected veteran status, disability status, or any other status protected by federal, state, or local law.
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Seagen
Seagen is an Equal Opportunity Employer
Submitted: 12/25/2020
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