Chinook Therapeutics

Sr. Research Associate, Biology

Biology (200) - Vancouver, British Columbia

Company:

Chronic kidney diseases are a severe and growing worldwide problem with a lack of effective treatments often leading to dialysis, transplantation, and high costs to health care systems. Up to 10% of the global population suffers from kidney disease and in the U.S. alone, kidney diseases account for over $130 billion in annual costs.

At Chinook Therapeutics our purpose is to discover and develop precision therapies to preserve kidney function and make dialysis and transplant unnecessary for people living with kidney disease. We strive for excellence in all we do and think big in our innovation; our highest priority is to do the right thing for patients while working together and having a whole lot of fun!

Our pipeline of precision medicines targets rare, severe kidney disorders with few currently approved therapies. For more information on Chinook and our pipeline, check out our site www.chinooktx.com/about & www.chinooktx.com/pipeline. We trade on Nasdaq under the ticker symbol KDNY and are headquartered in Seattle, WA with offices in Vancouver, BC, and Oakland, CA.

We seek applicants from all backgrounds to ensure we get the best, most creative talent on our team. We are building a diverse and inclusive workforce –come and be a part of our growth.

At Chinook, we are building a diverse, equitable, inclusive, and innovative company and we are looking for the BEST candidate for the job. That candidate may be one who comes from a less traditional background or may meet the qualifications in a different way. We would strongly encourage you to apply – especially if the reason you are the best candidate is not exactly as we describe it here.

Position:

Chinook Therapeutics is seeking a collaborative Sr. Research Associate to join the Translational and Target Biology team at our site in Vancouver, Canada. This role will be responsible for designing, performing, and analyzing in vitro experiments to support identification of new targets, expand on findings from translational human datasets and support building out new technologies, like state-of-the art organoid and cell-based systems. Hands-on experience in cellular biology, molecular biology, and enzymology is required. The ideal candidate will demonstrate strong teamwork and communication skills, will be able to design and perform experiments independently, and will propose innovative solutions to biological questions. The person in this role will work within a multidisciplinary drug discovery team to advance project goals.

Responsibilities include:

• Design, perform, and analyze in vitro experiments to support new target identification
• Establish and execute assays to analyze Pharmacodynamic (PD) and translational biomarkers in preclinical samples
• Collaborate with a multidisciplinary research team to design and execute PD and efficacy analysis on in vivo samples
• Proactively review research literature and contribute to overall project strategy
• Participate in and present data in team meetings
• Mentor other research professionals; may manage team members including co-op students
• Contribute to development and maintenance of a positive team-focused company culture

Location:

Chinook has offices located in Seattle WA, Oakland CA, and Vancouver BC

• This is an on-site position located in Chinook's Vancouver BC office.

Education, Experience, and Skills:

Required

• Strong working knowledge of cellular biology and molecular biology. Hands-on experience establishing cell culture platforms and/or cell-based functional assays
• B.Sc. degree with at least 5 years of post-graduate experience in an industry or academic setting
• Hands-on experience in key biological techniques (e.g., qPCR, ELISA, Western blotting, and/or immunohistochemistry, immune cell culture, flow cytometry)
• Hands-on experience with primary cell culture with preference for primary kidney cell culture expertise (e.g. podocyte systems, endothelial cells, proximal tubule cells)
• Demonstrated history of learning and establishing new laboratory techniques independently
• Ability to analyze, interpret, and communicate data in a clear manner

Preferred:

• Experience establishing and implementing high-throughput techniques for molecular biology and cell biology applications
• Experience with iPSC differentiation protocols and Organoid development
• Experience establishing and evaluating 3D Cell-Culture Systems
• Knowledge in renal cell biology mechanisms underlying kidney disease and/or Inflammation/autoimmune disease
• Effective time management skills and ability to work in a fast-paced team environment, meet deadlines, and prioritize work
• A strong team player with a passion for science and drug discovery
• Scientific curiosity, positive attitude, and high personal and ethical standards
• Demonstrated ability to mentor and train others

Salary Range: $100,000 - $117,000

Benefits:

• Paid parental leave
• Vacation and Sick time
• Living organ donor leave
• Volunteer time off
• 15 Paid Holidays
• Hybrid Work
• Flexible scheduling
• Healthcare plans
• Retirement Matching
• Financial wellness programs
• Employee assistance programs (EAPs)
• Internal learning & development courses

Chinook is an Equal Opportunity Employer, and we prohibit discrimination or harassment of any kind. We are committed to fostering an environment where ALL people are welcome and supported. We respect and value different experiences and viewpoints. We act respectfully toward one another and embrace diversity of people and ideas. Having a diverse workforce made up of team members who bring a wide variety of skills, abilities, experiences, and perspectives is essential to our success. Creativity and innovation flourish in an environment of openness, inclusion, and mutual respect.

To Apply:

Chinook Therapeutics

Chinook Therapeutics is an Equal Opportunity Employer

Submitted: 02/04/2023